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Tag Archives: immune

Immune therapy takes a ‘BiTE’ out of brain cancer

Building on their research showing that an exciting new form of immunotherapy for cancer has activity in patients with glioblastoma, the most common and most deadly form of brain cancer, Massachusetts General Hospital (MGH) investigators have created a new method

First impressions go a long way in the immune system

First impressions are important—they can set the stage for the entire course of a relationship. The same is true for the impressions the cells of our immune system form when they first meet a new bacterium. Using this insight, Weizmann

A genomic barcode tracker for immune cells

Researchers from the Garvan Institute of Medical Research have developed a new method to spot rare immune cells that are reactive against cancer cells, from within a patient’s own immune system. The patented ‘RAGE-seq’ method enables scientists to track how

Women’s stronger immune response to flu vaccination diminishes with age

Women tend to have a greater immune response to a flu vaccination compared to men, but their advantage largely disappears as they age and their estrogen levels decline, suggests a study from researchers at the Johns Hopkins Bloomberg School of

Holes in the immune system left unrepaired despite drug therapy

If they don’t receive antiretroviral therapy (ART), most HIV patients see a progressive weakening of their immune system. But a very small percentage of patients—0.3%—spontaneously control the virus themselves, without ART. Could an explanation lay partly in the sets of

Researchers survey immune molecules found inside mycetoma lesions

Mycetoma is a common neglected disease caused by either fungi or bacteria which organize themselves into grains—areas of inflammation surrounded by a collagen capsule. Now, researchers reporting in PLOS Neglected Tropical Diseases have studied two immune molecules inside these grains

Immune system effectiveness appears key to antibiotic success against persistent bacteria

Mathematical modeling suggests that the rate at which a patient’s immune system clears slow-growing variants of methicillin-resistant Staphylococcus aureus (MRSA) bacteria is a key determinant of whether antibiotics can cure the infection. Tsuyoshi Mikkaichi and Alexander Hoffmann of the University

Unconventional immune cells trigger disturbed cytokine production in human spondyloarthritis

Scanning electron micrograph of a human T lymphocyte (also called a T cell) from the immune system of a healthy donor. Credit: NIAID Spondyloarthritis is one of the most common types of chronic joint inflammation, affecting nearly 1 to 2

Unconventional immune cells trigger disturbed cytokine production in human spondyloarthritis

Scanning electron micrograph of a human T lymphocyte (also called a T cell) from the immune system of a healthy donor. Credit: NIAID Spondyloarthritis is one of the most common types of chronic joint inflammation, affecting nearly 1 to 2